Pathway-level visualization of the gene expression data is essential
for the systematic understanding of the inner activities of cells.
For this purpose, we present a tool for mapping transcriptome data
onto KEGG pathways and for creating a web-based database with an
overview of the entire pathway. Several databases of transcriptome
data obtained at Mori Laboratory, Nara Institute of Science and Technology,
Japan, are also presented below.
Publication (Click here to proceed)
Our manuscript describing this online resource is published by In Silico Biology journal with the title, "KEGG-based pathway visualization tool for complex omics data". Click the above "Publication" to view the full-text of the manuscript.
Pathway Visualization Web Application (Click here to proceed)
With this CGI-based web application, you can map your own data onto the KEGG pathway and generate the FLASH graphics. Heteromeric enzymes are correctly mapped with multiple gene components, and metabolic, transcriptomic, and proteomic data can be mapped simultaneously.
Sample Data (click on the image to enlarge):
Pentose Phosphate Pathway
Database: Systematic transcriptome analysis of two-component system in Escherichia coli
Oshima, T., Aiba, H., Masuda, Y., Kanaya, S., Sugiura, M., Wanner, B.L., Mori, H., Mizuno, T., "Transcriptome analysis of all two-component regulatory system mutants of Escherichia coli K-12", Mol Microbiol, 2002;46(1):281-291. PMID:12366850
Original Data: available at GenoBase.
This data is a systematic transcriptome analysis of 36 two-component deletion mutants of E.coli K-12 W3110.
Database: Systematic transcriptome analysis of 125 deletion mutants in Escherichia coli
Reference: in preparation.
This data is a systematic transcriptome analysis of 125 deletion mutants of E.coli K-12 W3110.
(C) 2004-2005 Nara Institute of Science and Technology & Institute for Advanced Biosciences, Keio University
KEGG Data used in this website is licensed by Pathway Solutions Inc.