Re-annotation of genomes using Restauro-G

All genomes used in Genome Projector are re-annotated using Restauro-G software.

Basically, Restauro-G is a very rapid genome re-annotation software for protein coding sequences, utilizing similarity searches based on BLAST-like Alignment Tool (BLAT) against UniProt KnowledgeBase (SwissProt and TrEMBL), NCBI nr, NCBI COGs, and other numerous public databases. Re-annotation by Restauro-G adds many useful information to RefSeq/EMBL complete genome flatfiles including the following:

  • additional function, catalytic activities, or notes from UniProt KB
  • Gene Ontology Terms
  • Links to many databases, such as NCBI gi, UniProt, PFAM, NCBI COGs, EC numbers, InterPro, TIGRFAM, GenomeReviews
  • protein subcellular localizations obtained from PsortDB

Restauro-G does *NOT* re-annotate RNA genes (tRNA/rRNA). Original annotation described in the RefSeq/EMBL flatfile is used in Genome Projector for RNA genes.

For the details about Restauro-G software, please see the following manuscript:

  • “Restauro-G: A Rapid Genome Re-Annotation System for Comparative Genomics”, Tamaki S, Arakawa K, Kono N, Tomita M, Genomics Proteomics Bioinformatics, 2007, 5(1): 53-58. (PubMed)

or the project web site

restauro.txt · Last modified: 2009/04/19 15:41 (external edit)